Corporate Social Responsibility is becoming ever more important in these challenging economic times. Real prosperity requires a combination of economic development with social generosity and demands a new approach towards social and managerial engagement. Mergers and acquisitions are typically complex in nature and have to be seen from a wider perspective that takes into account not just business, but also social, human and cultural dimensions as well. The right strategic approach and regard for Corporate Social Responsibility are important preconditions for a successful merger. The fulfillment of these preconditions can create greater shareholder value and strengthen Corporate Social Responsibility. Acting as a responsible corporate citizen does pay off, and the syndrome of selfishness can be overcome – at least partly.